Why Engineering a virus is 'impossible'!
Why Engineering a virus is 'impossible'!
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@Thunderf00t Says:
..... to anyone typing 'gain of function'....... thanks for showing us you never watched the video!
@PravinDahal Says:
Bioengineering does not work like mechanical engineering, in that you don’t build from ores, but you engineer starting from virus that already exists. You can splice genes for example, or use artificial selection to select preferred behavior.
@makeracistsafraidagain Says:
The White Plague came out in 1982 by Frank Herbert. My wife has a PhD in Molecular Biology. She pulled genetic material from one plant species and put it into another plant species. So I asked her if it was possible to engineer a virus to kill a select part of the human population. She said “no”. We are apparently too homogeneous.
@malikcurriah241 Says:
Much respect to the alchemist for this one. Covid Madness haunted people for years. Now some of us see magic.
@declanosullivan8749 Says:
We can’t even record a real time video of a virus infecting one of us from a sneeze 🤧. Never mind creating the bloody thing 😅 How can you create something if you can’t even see it 🤔 chat see it living and replicating 😮
@tusse67 Says:
Thunderf00t is turning into the cat lady of science!
@wadewilson6628 Says:
So you're using semantics to prove your point. Im guess you haven't seen the leaked call records where high ranking memebers of the CDC and WHO admited it was a bioweapon lab leak.
@michellelewis3063 Says:
The frequency of your use of logical fallacies is unbefitting. Your allegiance to prior held beliefs in defiance of new information is disappointing.
@Kai...999 Says:
Idk, im just a mechanical engineer and im well aware of the dunning Kruger effect, but i think they can engineer viruses. I mean your logic is just... Off base. Like we can make a shit ton of dog breeds from the grey wolf. We literally can just brute force it .
@bryandraughn9830 Says:
Man, don't you know that everyone instantly became a virology expert a couple of years ago? What's weird is at the exact same moment every doctor in the world forgot everything they had ever learned. Just ask any one of these lobotomized brain stumps and they'll tell you all about it.
@BeetleJuice1980 Says:
This channel is gold, it deserves more subs and likes.
@RoarOfWolverine Says:
No animal on earth can digest cellulose. All animals that eat plants need bacteria in their guys to ferment cellulose, but that still doesn’t completely digest it. Ruminant animals, who are the most efficient at getting nutrients from grasses, also need to mechanically crush the cells by chewing. They also need flat molars and long side to side jaw movement in order to grind the plant material, like a grinding stone. Even still, they must bring the material back up to their mouths to chew it more, then send it to a different chamber in their stomachs and they do this four time, if you’re talking about cattle. Each stomach chamber have different flora, including bacteria, fungus and protozoa in each stomach which ferment the cellulose again and again until it reaches the rumen chamber where the serious fermentation takes place. That is the best nature could come up with for breaking down cellulose. Termites also rely on flora within their intestines to digest the cellulose and they’re the best thing nature could create for breaking down the hardest cellulose, which are just very tough carbohydrates. Without termites, large trees would take way, way longer for bacteria alone to do the work.
@raketman101 Says:
furin cleavage site 🎉
@floydmayflower Says:
im loving these comments. "thunderfoot" has always been full of shit and he's geting roasted in the comments by experts in this field. many of his videos are littered with the same level of misinformation and incidences of completely missing the point so badly it's hard to believe it's not on purpose, it's just that you are not an expert in those domain, so you couldn't tell. worse, many are about elon, so any attempt to inform of said misinformation in the comments only results in elon haters dogpiling. you can't get any information past the accusations of being an elon lover. this guy is not a reliable source of information. you've all been conned. stop watching this loser. he's an ideologue who cannot see past his own biases.
@Listoic Says:
You're making a semantics argument, not a scientific one. Sloppy.
@FennecTECH Says:
theres a guy on YouTube who bioenginered and manufactured retrovirus to give him a functional lactace gene and had significant success mitigating his own lactose intolerance.
@SandyRiverBlue Says:
I hope I'm not the only one that has pointed out that what John was doing there is called irony. He doesn't believe that the virus was entirely constructed in a lab to do what it did. But viruses are being tampered with in a more iterative way. You can expose a lot of different viruses to a lot of different chemical agents, then insert them into egg medium to increase their count, then test them one by one for what they do. On top of that you can continuously sample new mutated strains from the wild and test those for what they can do. We do it all the time, it's the foundation of virology. That said, the reason I don't think China did this on purpose is that they were the hardest hit. They were in the middle of an economic bubble collapse and could ill afford to shut down their country. Add to that their zero COVID policy and you'd have to be generous to think it was done on purpose. Personally I think it was done on accident, from a wild strain that escaped the lab on someone's lapel or shoe, or in their respiratory system.
@duncantalksalot Says:
Just wish to quickly point out that whole Jon Stewart segment was a bit
@IloveJellow Says:
you can not engineer a virus but you can adjust how it works and also evolve and watch the effects in turn you can to a degree make it do the exact same thing it already does but better. Engineering a virus would imply you built it from the ground up which isn't possible as of now... Not saying that wohan wasn't doing things they shouldn't have been doing.
@themeantuber Says:
We can't 'engineer' a virus?! Well, as chairman Mao says, we'll solve our problems with what we've got! We warned you not to interfere with our internal affairs or you'll face consequences. And now, I don't see anyone talking about the Hong Kong protests after the virus broke out. In any case, the virus is not our fault.
@sebastienleblanc5217 Says:
lay people have really just replaced religion with scientism, they think scientist are essentially gods or have god like powers...
@CarlosBunn Says:
Dude just watch the tought emporium video where he engineered a virus to temporarly cure his lactose intolerance
@vollkerball1 Says:
04:52 yup that would be it.
@androidemulator6952 Says:
"I say we take off and nuke the entire site from orbit ... It's the only way to be sure.." Ripley "Aliens". gets me every time! ;)
@OdaSwifteye Says:
What I got from this is that the Chinese lab workers were experimenting on something that was impossible to do.
@statego Says:
If it is so obvious why make and release this video now after so much time has gone by ?
@sranprodanovic6616 Says:
I'm not a molecular biologist, but I have the following intuition. I might well be wrong. Not sure, so posing it as a question: Isn't increase in successful self-replication a very evolutionary goal of viral microorganisms, which would make breeding such organisms through mutation and selection a lot easier than the needle-in-haystack problem of synthesizing a novel cellulose-hungry enzyme? It is my understanding that cellulase enzymes aren't that good at the thing, presumably due to a poor reward for the function they perform, resulting in us dispatching most of the fibers we ingest together with the rest of the anorganic matter after metabolising. Thank you for consideration, and the rest of the content you create on your channel.
@pbnaj Says:
You can't destroy a virus either....so
@Skullringer09 Says:
This was to logical for conspiracy theorist. Time for them to blame the jews.
@SergyMilitaryRankings Says:
Phil you're going to get the rabid anti china bots coming after you Edit: they already came lmfao
@zeusnitch Says:
Insoluballose...nice shoutout to potholer :-)
@investoroncoke Says:
This a moronic straw-man. The argument is that the wu flu escaped from the wuhan lab, which was then covered up.
@Nitsirtriscuit Says:
Thunder foot should really familiarize himself with TheThoughEmporium before making such a lazy video about bioengineering. His condescending attitude and expertise in his own field mixed with the success of a YouTube channel have turned him into a scientific laughing stock the moment he steps outside of criticizing Elon. While not being technically wrong on any point if you take a certain perspective about semantics, he’s ended up trivializing and downplaying the concepts so badly that people who haven’t studied it will get the wrong idea. I’d say to leave your politics at the door and take a college class in microbiology, but unfortunately colleges are full of politics and maybe at this point they’ve walked back the unit on CRISPR.
@csm5729 Says:
WOW this video popped an internet bubble of crazies.
@Mrch33ky Says:
As I live and breathe! Entering Mr. Beast levels of irrelevant wankery with this one. If only you hadn't you passed on the path of a Classical Education, my wicked son.
@harrycartmel Says:
thank you
@Gigika313 Says:
4:15 🤦🏻‍♂️ sars 1 was literally first detected in Kansas at a military base in 1919 hence the name Covid 19 (sars 2) 👍🏼
@starblaiz1986 Says:
Sorry commentors, but Phil is right on this one. 1) "BuT wE bReEd DoGs!" sure, but a) Viruses don't breed, they multiply and mutate - a very different and way harder to control process. And b) Dogs still have the fundamental wolf form and behaviours of their ancestors. If there were six-legged giraffe-necked bat-eared dogs running around, it might be a different story, but there isn't. "Guided evolution" - to the degree that we can do it - is still very limited. This applies doubly to viruses, which are naturally unstable and are fantastic at evading control. 2) "But they could have spliced different parts of viruses together!" True (with a lot of limitations), but every known technique for doing that leaves behind very obivous signs, none of which were seen by the dozens of independant virologist teams around the world when they independantly sequenced the virus' genomes. Every one of those teams has shown that Covid19's unique features, which allow it to bind effectively to human cells, appear to be the result of natural selection, not laboratory manipulation. The virus's structure does not match any previously known virus backbones used in research labs, which suggests it came from natural sources, likely wildlife. Additionally, the complex adaptations seen in the virus, such as the efficiency of its spike protein at infecting human cells, were unlikely to have been pre-identified or engineered by scientists, as these adaptations represent a sophisticated level of natural evolution that wouldn't be chosen arbitrarily for lab experiments. While scientists can engineer viruses to gain certain functions, the specific set of adaptations seen in SARS-CoV-2 (Covid19) are complex and suggest a fine-tuning that typically comes from a natural evolutionary process, rather than from direct human design.This evidence supports the conclusion that Covid19 evolved naturally, without any human intervention. None of this is any kind of secret either. Research teams around the world were highly transparent and collaborative about their research. So unless China is decades more advanced in technology than every other nation on the planet to where they can manipulate viruses AND ALSO make them look COMPLETELY NATURAL while doing so, then it's was a naturally occuring virus. And if they do have that kind of wildly advanced Clarketech-level technology, then we had better all start learning the Chinese national anthem, because in that case this is the CCP's world, we're all just living in it! 😅 3) If they really were doing the kind of "weaponization" research that people claim, wouldn't you think they would have been way out in front with developing thier vaccines? Instead, the US (Pfizer–BioNTech) and UK (Oxford–AstraZeneca) were the first to release vaccines to the general public, with China (Sinopharm BIBP) close behind (key word there - BEHIND). And China's vaccines were only 50-60% effective, compared to the US's 95% and the UK's 90%. That goes against the notion that they had any kind of foreknowledge, which you would expect them to have if they were developing it on purpose. 4) "But hurricane research labs don't have hurricanes!" Okay cool and all, but you can apply the same idea to any research lab, including ones that do house the thing they are researching. The Berkeley Fire Research Lab for example is located in Callifornia. Callifornia is known for its forest fires. CoInCiDeNcE?!? 😂 Or is it just that they said "Hey, we get a lot of forest fires here, we should maybe set up a lab to study that"? 😊 So yeh, sorry guys, but there's no conspiracy here. Just a naturally occuring virus in an area that has a lot of that family of virus' about. The lab was near by because obviously a lab is going to be stationed near to the thing that it wants to be researching if possible, like Phil said with regards to hurracane research labs being near where hurricanes occur.
@dreadboy5314 Says:
This video was jarring. I love this channel but this video is so off the mark and misleading from a creator who is usually very insightful and thorough in navigating his topics. I cant tell if the premise for this video is intentionally dense or just a misunderstanding of the topic by the creator but both possibilities are pretty hard to comprehend. Disliked and reported for misinformation
@supersynth818 Says:
I didn't realize Tsunamis begin with a patient zero.
@stormsabre22 Says:
14:32 "evade group behaviour like social distancing or masks" does Thunderf00t know what a Cochrane review is ? The only group behaviour that works is quarantine.
@satouhikou1103 Says:
Fauci killed dogs.
@mrdumbfellow927 Says:
This guy just keeps showing how much more he is interested in proving a PERSON wrong, rather than proving a fact correct. He'll always use someone's statements in poor faith if he wants to prove his point. Any science requiring some subjective interpretation is going to get the WORST take from him when it is Elon Musk, etc. Jon Stewart makes a JOKE about how it's not exactly IMPOSSIBLE for a new virus to come from a lab mistake .....a lab located in the middle of the outbreak that just happens to work with that exact type of pathogen........😂 that's all. He was ridiculing people that responded to that possibility in absurd fashion. Its like me finding trash on the road by neighborhood dump. I don't KNOW for sure if it blew out of the dump or out of someone's car, but certainly thinking it COULD BE FROM THE DUMP IS REASONABLE! Especially if the dump DOESN'T ALLOW YOU TO CHECK AND SEE IF THEY HAVE PROBLEMS WITH TRASH BLOWING AWAY! (CHINA)😂 Thunderf00t attacks an argument was that wasn't even being made. It blows my mind that people can't see how tainted and emotional his "science" has become. I'm pretty sure Elon Musk could cure cancer while other billionaires eat children, and Thunderf00t would focus on how Musk cured cancer wrong😂
@steffenrumpel2784 Says:
A little late to the party, but still ... If we had evolved to a point where we would know how to avoid doing stupid things, then how come we spent a considerable amount of resources to develop nukes? Do we intend to ever use them? If not, then why would you waste all the resources to maintain them? Doesn't that qualify as "stupid"? Also, not every country has managed to leave the 1950s behind. Just look at a certain war that is still an ongoing issue in Europe to this very day.
@phoenixnair Says:
Your whole analogy with cellulase is just dumb on so many levels!
@skinny_pp Says:
Med student here. Not gonna comment on genetic engineering as I have no clue. I just like to mention that SARS coronaviruses, among other diseases, have been speculated to eventually cause outbreaks and potentially serious pandemics (as happened) due to their increased virulence and ability to cause severe acute respiratory syndrome (SARS) and acute respiratory distress syndrome (ARDS) (the second requires intubation). Nevertheless this has also been reported by my father (also a dr.) as he read when he was studying medicine many years ago. I’m too bored to search the references, but if you guys notice this I’ll try my best.
@jimmyincredible3141 Says:
Yes, the lab is close to the place of discovery...now lets think about that logically: Will your local doc be able to identify that you have a novel, so far unidentified, virus if you show up with influenza symptoms? Nope - most likely there won't even be a test for the flu-virus - you get the influenza meds and are sent home. Now when is the logical point where someone actually gets suspicious that its not the flu? Exactly - when the infection crosses path with actual experts - most likely spot being close to their workplace... Its really not that far fetched. The only thing that would imply is that it might have been circulating earlier than originally thought...
@MarkusAT Says:
Might be that I'm completely wrong, but wasn't the whole issue because of the lack of precautions and bad practices that raised the alarm? I don't remember any sane person saying that the virus was really intended to be used as a weapon.
@tahoeclimber Says:
Why did all covid patient deaths only happen in hospitals?????? I personally never took Trump's warp speed Israeli Zionist pharma derived Biden mandated vax, and somehow I survived unscathed. I never experienced anything other than my usual annual colds etc, even after being exposed to people who dubiously tested positive with covid. I was so sure it was bs I never masked or refrained from physical contact, even with allegedly positive tested people. It was another grand psyop where the perpetrators literally made trillions, disenfranchised the masses, and further undermined the concept of science as a philosophical discipline.
@bluntdude Says:
Impossible? You mean extremely difficult , Not impossible.

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